We are dedicated 

to furthering open genome science & technology.

The Computational Genomics Lab is a shared venture


led by faculty, research scientists and engineers within the


UC Santa Cruz Genomics Institute.

What We Do

Our research is currently focused on:


Building technology to connect the institutional silos where genome information is now isolated by forging and implementing interoperable standards. We are a proud members of the Global Alliance for Genomics and Health.

    • Comparing the history of vertebrate genomes. Want to reconstruct a 65 million old genome from the genomes of its descendants? Talk to us! We love the Genome 10K, a project to sequence 10,000 vertebrate genomes.
    • Using next-next generation sequencing technology to create more complete, accurate and phased genomes.
    • Making it easy to discover and share portable, reproducible and scalable genomic workflows.
    • Analyzing massive genomic datasets using the cloud.
    • Build a human reference genome structure that contains all common variation as a universal basis for genomics.
    • Completing the library of human and mouse RNAs.


We recruit graduate students in the UCSC Biomolecular Engineering and Bioinformatics (BMEB) and the
Department of Computer Science (CS) Graduate Programs at UC Santa Cruz’s Baskin School of Engineering.