DNA sequencer the size of a mobile phone

By Branwyn Wagman, UC Santa Cruz Genomics Institute Investigators at the UC Santa Cruz Genomics Institute have optimized performance of a mobile-phone-sized MinIONTM DNA sequencer, marketed by Oxford Nanopore. Their work was reported in Nature Methods on February 16,...

Improved data analysis for the MinION nanopore sequencer

Abstract Speed, single-base sensitivity and long read lengths make nanopores a promising technology for high-throughput sequencing. We evaluated and optimized the performance of the MinION nanopore sequencer using M13 genomic DNA and used expectation maximization to...

2015: Year of the Genome Map? Maybe so, Says Simons.

It’s no secret that genetics is hot right now, especially in the brain realm. The biggest story of 2014 was Ted Stanley’s stunning $650 million gift to mental health research at the Broad Institute, a research center that grew out of the Human Genome Project. But...