UCSC Xena

UCSC Xena is a bioinformatics tool to visualize functional genomics data from multiple sources simultaneously, including both public and private data. The Xena system consists of a set of federated data hubs and the Xena browser, which integrates across hubs,...

High Throughput Genomics Group

Genomics is in transition. The growth in data—driven by the need for vast sample sizes to gain statistical significance and the explosion of clinical sequencing—is far outpacing Moore’s law. Large projects like The Cancer Genome Atlas have generated petabyte scale...

Genome 10K

The vertebrate evolutionary tree The Genome 10K project aims to assemble a genomic zoo—a collection of DNA sequences representing the genomes of 10,000 vertebrate species, approximately one for every vertebrate genus. The trajectory of cost reduction in DNA sequencing...

GENCODE

View of a 56 Kbp region of human chromosome 17 where GENCODE annotates one non-coding and 5 protein coding genes. Two genes in the region display tissue-specific gene expression as evidenced by GTEx RNA-seq. The TCAP (titin cap protein) is highly expressed in muscle...

Computational Nanopore Genomics

Nanopore technology is emerging as one of the leading contenders for next generation sequencing. The concept of nanopore sequencing was envisioned in the early 1990s by David Deamer (UC Santa Cruz) and Daniel Branton (Harvard). The recent commercialization of the...