Telomere-to-telomere assembly of a complete human X chromosome
Karen H Miga, Sergey Koren, Arang Rhie, Mitchell R Vollger, Ariel Gershman, Andrey Bzikadze, Shelise Brooks, Edmund Howe, David Porubsky, Glennis A Logsdon, Valerie A Schneider, Tamara Potapova, Jonathan Wood, William Chow, Joel Armstrong, Jeanne...
TrawlerWeb: an online de novo motif discovery tool for next-generation sequencing datasets
By: Dang LT, Tondl M, Chiu MHH, Revote J, Paten B, Tano V, Tokolyi A, Besse F, Quaife-Ryan G, Cumming H, Drvodelic MJ, Eichenlaub MP, Hallab JC, Stolper JS, Rossello FJ, Bogoyevitch MA, Jans DA, Nim HT, Porrello ER, Hudson JE, Ramialison M. Abstract BACKGROUND: A...
R2C2: Improving nanopore read accuracy enables the sequencing of highly-multiplexed full-length single-cell cDNA
By: Roger Volden, Theron Palmer, Ashley Byrne, Charles Cole, Robert J. Schmitz, Richard Edward Green, Christopher Vollmers Abstract High-throughput short-read sequencing has revolutionized how transcriptomes are quantified and annotated. However, while Illumina...
A graph-based approach to diploid genome assembly
By: Shilpa Garg, Mikko Rautiainen, Adam M Novak, Erik Garrison, Richard Durbin, Tobias Marschall Abstract Motivation Constructing high-quality haplotype-resolved de novo assemblies of diploid genomes is important for revealing the full extent of structural variation...
A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence
By: Camila Ferreirade Souza, Thais S. Sabedot, Tathiane M. Malta, Lindsay Stetson, Olena Morozova, Artem Sokolov, Peter W. Laird, Maciej Wiznerowicz, Antonio Iavarone, James Snyder, Anade Carvalho, Zachary Sanborn, Kerrie L. McDonald, William...
Recommendations for the packaging and containerizing of bioinformatics software [version 1; referees: 2 approved with reservations]
By: Bjorn Gruening, Olivier Sallou, Pablo Moreno, Felipe da Veiga Leprevost, Hervé Ménager, Dan Søndergaard, Hannes Röst, Timo Sachsenberg, Brian O'Connor, Fábio Madeira, Victoria Dominguez Del Angel, Michael R. Crusoe, Susheel Varma, Daniel Blankenberg, Rafael C....